Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.600 Biomarker disease RGD Effects of melatonin on cytokine release and healing of colonic anastomoses in an experimental sepsis model. 27598601 2016
Entrez Id: 133
Gene Symbol: ADM
ADM
0.600 Biomarker disease RGD Human adrenomedullin and its binding protein ameliorate sepsis-induced organ injury and mortality in jaundiced rats. 20132852 2010
Entrez Id: 836
Gene Symbol: CASP3
CASP3
0.600 Therapeutic disease RGD Glutamine reduces myocardial cell apoptosis in a rat model of sepsis by promoting expression of heat shock protein 90. 29180187 2017
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.600 Biomarker disease RGD [Effects of antimicrobial agents on the Toll like receptors and myeloid differentiation protein-2 in liver tissue of alcohol-induced liver disease: experiment with rats]. 19489280 2009
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.600 Biomarker disease RGD [Changes in Toll-like receptor 2 and 4 gene expression in vital organs in septic rats and their regulation mechanisms]. 14604479 2003
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
0.600 Therapeutic disease RGD Neutralization of receptor for advanced glycation end-products and high mobility group box-1 attenuates septic diaphragm dysfunction in rats with peritonitis. 19623040 2009
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.600 Biomarker disease RGD Suppression of hepatic cytochrome p450-mediated drug metabolism during the late stage of sepsis in rats. 15665729 2005
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.600 Therapeutic disease RGD Effects of Pseudomonas aeruginosa mannose-sensitive hemagglutinin (PA-MSHA) pretreatment on septic rats. 24055021 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.600 Biomarker disease RGD Suppression of hepatic cytochrome p450-mediated drug metabolism during the late stage of sepsis in rats. 15665729 2005
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.600 Therapeutic disease RGD Effects of Pseudomonas aeruginosa mannose-sensitive hemagglutinin (PA-MSHA) pretreatment on septic rats. 24055021 2013
Entrez Id: 5624
Gene Symbol: PROC
PROC
0.600 ModifyingMutation disease RGD Evaluation of protein C and other biomarkers as predictors of mortality in a rat cecal ligation and puncture model of sepsis. 15241104 2004
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.600 Biomarker disease RGD Paeoniflorin inhibits systemic inflammation and improves survival in experimental sepsis. 19371254 2009
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.600 Biomarker disease RGD [Changes in expressions of the myocardial Toll-like receptor 4, tumor necrosis factor-alpha and interleukin-6 mRNA in rat with sepsis]. 19695174 2009
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.540 Therapeutic disease RGD Matrix metalloproteinase-2 and metalloproteinase-9 activities are associated with blood-brain barrier dysfunction in an animal model of severe sepsis. 23479197 2013
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.300 Therapeutic disease RGD Activated protein C alters inflammation and protects renal function in sepsis. 21429520 2011
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.300 Biomarker disease RGD Effects of melatonin on cytokine release and healing of colonic anastomoses in an experimental sepsis model. 27598601 2016
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.300 Biomarker disease RGD A model of experimental acute hematogenous pyelonephritis in the rat. 21797109 2011
Entrez Id: 177
Gene Symbol: AGER
AGER
0.300 Therapeutic disease RGD Neutralization of receptor for advanced glycation end-products and high mobility group box-1 attenuates septic diaphragm dysfunction in rats with peritonitis. 19623040 2009
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.300 Biomarker disease RGD [Changes in Toll-like receptor 2 and 4 gene expression in vital organs in septic rats and their regulation mechanisms]. 14604479 2003
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.300 Biomarker disease RGD CpG oligodeoxynucleotide protection in polymicrobial sepsis is dependent on interleukin-17. 15776385 2005
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.300 Biomarker disease RGD Sepsis-induced inflammation is exacerbated in an animal model of type 2 diabetes. 19079684 2008
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.300 Biomarker disease RGD [Effects of antimicrobial agents on the Toll like receptors and myeloid differentiation protein-2 in liver tissue of alcohol-induced liver disease: experiment with rats]. 19489280 2009
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.300 Therapeutic disease RGD Anti-c5a ameliorates coagulation/fibrinolytic protein changes in a rat model of sepsis. 12000738 2002
Entrez Id: 2152
Gene Symbol: F3
F3
0.300 Therapeutic disease RGD Sodium tanshinone II A sulfonate ameliorates microcirculatory disturbance of small intestine by attenuating the production of reactie oxygen species in rats with sepsis. 26311287 2016
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.300 Therapeutic disease RGD [Effect of oxymatrine on JAK2/STAT3 signaling in renal tissues of rats with septic shock]. 24228589 2013